Institute of Organic Chemistry

5 Murmanska St., 02660, Kyiv, Ukraine

Phone: (044) 552 7150; fax: (044) 573 2643;
e-mail: ioch@bpci.kiev.ua;
http://www.ioch.kiev.ua

Principal study areas:

– theoretical and experimental research into the structure, chromaticity and reactivity of organic compounds;

– fine organic synthesis;

– chemistry of heteroatom organic compounds;

– supramolecular chemistry of macrocyclic compounds;

– chemistry of physiologically active substances, scientific fundamentals of the synthesis of compounds with practically useful properties, including cyanine dyes, organic catalysts and complex-forming agents.

The Institute has science schools in:

– theories of chromaticity and cyanine dyes synthesis (founded by Acad. A. I. Kiprianov, nowadays headed by Prof. O. I. Tolmachov);

– mechanisms of organic reactions (founded by Acad. E. O. Shilov, at present headed by Prof. V. I. Staninets);

– chemistry of phosphorus-containing compounds (founded by Acad. O. V. Kirsanov, nowadays led by Prof. O. M. Pinchuk);

– chemistry of organo-fluorine compounds (headed by Prof. L. M. Yagupolsky);

– chemistry of biologically active substances (founded by Prof. P. S. Pelkis, nowadays led by M. O. Lozinsky).

The following research results are proposed for cooperative finalization and commercialization:

– development of ‘Yakton’ medical preparation (Pharmacology Dept. of the O. O. Bohomolets National Medical University);

– development of ‘Tomerzol’ medical preparation (Borshchahivsky Chemico-Pharmaceutical Plant);

– ‘Borizol’ anti-sclerotic preparation (6-trifluoromethoxy-2-aminobenzothiazole) was synthesized for the first time at NAS Institute of Organic Chemistry; it can penetrate the hemato-encephalic barrier and possesses neuro-protective properties.

– multi-channel sensor blocks (‘electronic nose’) on the basis of calixarene receptors for determining the chemical image of gas medium (smell). Name: ‘Analyzer of gas mixtures of the ‘Electronic Nose’ GAS-2 type. Purpose: For analyzing gas mixtures of organic substances, alcoholic and soft drinks, perfumes, toxic admixtures in the air. Action mechanism: a unit of quartz resonators is covered with films of organic sorbents (calixarenes, polymers), which have various sensitivities to certain class of volatile molecules to be analyzed. This system is a super-high-precision one, i.e., after injection of analyte vapours, the operating volume of the chamber is cut off from the atmosphere.